Pld2

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Activation of PC-specific PLDs occurs as a consequence of agonist stimulation of both tyrosine kinase and G protein-coupled receptors. PC-specific PLDs have been proposed to function in regulated secretion, cytoskeletal reorganization, transcriptional regulation, and cell cycle control. PLD2 is activated by substrate presentation. PC substrate is polyunsaturated and resides in the membrane separately from lipid rafts near phosphatidylinositol 4,5-bisphosphate PIP2.

PLD2 has been shown to interact with:. From Wikipedia, the free encyclopedia. Protein-coding gene in the species Homo sapiens. Golgi apparatus endoplasmic reticulum membrane membrane plasma membrane presynapse. Fc-gamma receptor signaling pathway involved in phagocytosis lipid metabolism cell motility small GTPase mediated signal transduction lipid catabolic process synaptic vesicle recycling cytoskeleton organization phosphatidic acid biosynthetic process inositol lipid-mediated signaling.

National Center for Biotechnology Information, U. National Library of Medicine. Cytogenetics and Cell Genetics. PMID S2CID The Journal of Biological Chemistry. Nature Communications. Bibcode : NatCo PMC July The Journal of Investigative Dermatology. FEBS Letters. June Journal of Neurochemistry. May March Molecular and Cellular Biology. September Journal of Medicinal Chemistry.

Biochemistry and Cell Biology. Golgi apparatus endoplasmic reticulum membrane membrane plasma membrane presynapse. Fc-gamma receptor signaling pathway involved in phagocytosis lipid metabolism cell motility small GTPase mediated signal transduction lipid catabolic process synaptic vesicle recycling cytoskeleton organization phosphatidic acid biosynthetic process inositol lipid-mediated signaling.

National Center for Biotechnology Information, U. National Library of Medicine. Cytogenetics and Cell Genetics. PMID S2CID The Journal of Biological Chemistry. Nature Communications. Bibcode : NatCo PMC July The Journal of Investigative Dermatology. FEBS Letters. June Journal of Neurochemistry. May March Molecular and Cellular Biology. September Journal of Medicinal Chemistry. Biochemistry and Cell Biology. Current Biology. November October The Biochemical Journal.

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